NVDIAG presented its advancements at AIS 2026

The NVDIAG LabCom team was very happy to be present at the 14th Antibody Industrial Symposium (AIS 2026) held in Montpellier on June 30 and July 1.  It was a special opportunity to share our work on the development of nano-antibodies (nAbs) from our cutting-edge platform using extracellular vesicles (EVs) for the presentation of native membrane proteins.

4 posters were in the spotlight :

Clara Bouyx presented the use of EVs as a dual platform for nano-antibody discovery and direct binding kinetics measurements on CD38, a key biomarker for multiple myeloma. Her demonstration proves that this technology allows for the revelation of native epitopes that are absent from classic soluble recombinant proteins. Check her poster

Cléa Vessiere detailed an innovative « phage display » strategy on EVs with epitope masking.  The objective? To identify non-competitive binders (such as NVD011) allowing for reliable quantification of CD38, even in the presence of therapeutic antibody treatments. Check her poster

Cassandre Vedel displayed her work on CD33, a target of interest in acute myeloid leukemia (AML). She presented the development of the NVD_110 nanobody, which is capable of specifically detecting a truncated isoform of the protein, opening new perspectives for patient diagnosis. Check her poster

Ellen Donker showcased an innovative method for the direct BLI screening of non-purified nanobodies from bacterial lysates. This optimized workflow enables early kinetic evaluation of candidates without prior purification, providing a major time-saving advantage in selecting high-affinity binders for conditions such as kidney diseases or dry eye disease. Check her poster

 

🌟 Training for the future

As we have mentioned in our previous posts, training the next generation of researchers is a central mission of the NVDIAG LabCom. Seeing Cléa and Cassandre carry our research projects to an international level perfectly illustrates this commitment.

Bravo to them for the quality of their work and their involvement! 👏