New Publication
Our LabCom at the heart of an international collaboration!
Clara Bouyx and Alain Roussel contributed to a study published in Cell Reports, alongside researchers from Nanyang Technological University Singapore, Singapore-MIT Alliance for Research & Technology, Synchrotron SOLEIL and Singzyme. B7-H3 (CD276) is a protein overexpressed in many solid tumors, where it plays a role in immune evasion and is associated with poor clinical prognosis. It is an attractive target for both diagnosis and therapy — and precisely one of the targets in our pipeline!
The generation of T3CL11, a nano-antibody specific for both human and mouse B7-H3, shows promising results for the detection of B7-H3-positive tumors in vivo in osteosarcoma and colorectal cancer models — paving the way for diagnostic imaging and theranostic applications.
These findings highlight the potential of our platform to turn complex immunological targets into innovative diagnostic tools.
